Hayato Hikita Selected Research

Pancreatitis

1/2018	Autophagy impairment in pancreatic acinar cells causes zymogen granule accumulation and pancreatitis.
12/2012	Pancreatic STAT3 protects mice against caerulein-induced pancreatitis via PAP1 induction.

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Hayato Hikita Research Topics

Disease

41	Hepatocellular Carcinoma (Hepatoma) 01/2024 - 05/2010
26	Neoplasms (Cancer) 01/2024 - 12/2008
17	Infections 01/2023 - 08/2011
13	Liver Cirrhosis (Hepatic Cirrhosis) 10/2022 - 06/2010
12	Chronic Hepatitis C 01/2023 - 01/2016
10	Fibrosis (Cirrhosis) 12/2023 - 03/2011
8	Inflammation (Inflammations) 10/2023 - 02/2010
5	Pancreatic Neoplasms (Pancreatic Cancer) 10/2023 - 01/2019
5	Hepatitis C 06/2022 - 12/2017
4	Chronic Hepatitis (Chronic Active Hepatitis) 01/2022 - 10/2008
4	Non-alcoholic Fatty Liver Disease 11/2021 - 01/2016
4	Hepatitis 01/2021 - 01/2007
3	Liver Diseases (Liver Disease) 01/2022 - 08/2015
3	Carcinogenesis 01/2022 - 08/2015
3	Fatty Liver 01/2021 - 07/2017
3	Adenocarcinoma 01/2020 - 07/2017
3	Cholestasis 03/2011 - 01/2008
2	Chronic Hepatitis B 03/2023 - 01/2016
2	Disease Progression 02/2022 - 05/2021
2	Virus Diseases (Viral Diseases) 01/2022 - 11/2015
2	Anemia 08/2019 - 02/2010
2	Massive Hepatic Necrosis 10/2018 - 01/2007
2	Pancreatitis 01/2018 - 12/2012
1	Stomach Neoplasms (Stomach Cancer) 04/2024
1	Hyperlipidemias (Hyperlipidemia) 01/2024
1	COVID-19 11/2023
1	Cholangiocarcinoma 01/2023
1	Cachexia 12/2022
1	Paraneoplastic Syndromes (Paraneoplastic Syndrome) 12/2022

Drug/Important Bio-Agent (IBA)

18	Antiviral Agents (Antivirals)IBA 12/2023 - 12/2017
17	Proteins (Proteins, Gene)FDA Link 12/2022 - 05/2010
8	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2016
7	Fetal Proteins (Fetoprotein)IBA 01/2024 - 10/2017
7	RNA (Ribonucleic Acid)IBA 10/2023 - 01/2017
7	SofosbuvirIBA 04/2023 - 11/2015
6	Sorafenib (BAY 43-9006)FDA Link 04/2021 - 05/2010
5	Bevacizumab (Avastin)FDA Link 01/2024 - 02/2022
5	atezolizumabIBA 01/2024 - 02/2022
5	Glycoproteins (Glycoprotein)IBA 01/2023 - 03/2011
5	InterferonsIBA 10/2020 - 03/2016
5	Small Interfering RNA (siRNA)IBA 07/2017 - 10/2010
4	CytokinesIBA 10/2023 - 11/2015
4	lenvatinibIBA 07/2022 - 11/2019
4	BilirubinIBA 09/2020 - 10/2009
4	sofosbuvir drug combination ledipasvirIBA 01/2020 - 12/2017
4	Transcription Factors (Transcription Factor)IBA 01/2020 - 12/2012
4	Ribavirin (Virazole)FDA LinkGeneric 08/2019 - 03/2016
3	VaccinesIBA 03/2023 - 12/2008
3	Hepatitis B Surface Antigens (HBsAg)FDA Link 03/2023 - 01/2016
3	Connective Tissue Growth FactorIBA 01/2023 - 08/2011
3	Phosphotransferases (Kinase)IBA 01/2023 - 10/2010
3	Growth Differentiation Factor 15IBA 01/2022 - 01/2021
3	ledipasvirIBA 01/2021 - 11/2015
3	Acetylcysteine (Siran)FDA LinkGeneric 01/2021 - 08/2015
3	SimeprevirIBA 07/2017 - 03/2016
3	Lamivudine (Epivir)FDA Link 05/2009 - 06/2008
2	velpatasvirIBA 04/2023 - 01/2021
2	Interleukin-6 (Interleukin 6)IBA 01/2023 - 02/2022
2	Messenger RNA (mRNA)IBA 12/2022 - 05/2010
2	pgRNAIBA 01/2022 - 01/2020
2	Hyaluronic Acid (Hyaluronan)IBA 01/2022 - 11/2021
2	AlbuminsIBA 01/2022 - 09/2020
2	HaptoglobinsIBA 01/2022 - 01/2016
2	Warfarin (Coumadin)FDA LinkGeneric 01/2022 - 11/2019
2	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2016
2	LipidsIBA 01/2022 - 12/2016
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 11/2021 - 01/2016
2	Nonesterified Fatty Acids (NEFA)IBA 01/2021 - 07/2017
2	asunaprevirIBA 01/2020 - 01/2020
2	daclatasvirIBA 01/2020 - 01/2020
2	micaIBA 10/2019 - 09/2012
2	Lipase (Acid Lipase)FDA Link 01/2018 - 12/2012
2	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2016 - 08/2015
2	CholesterolIBA 01/2016 - 11/2014
2	NucleotidesIBA 11/2015 - 01/2007
2	Cytostatic AgentsIBA 08/2012 - 10/2010
2	MicroRNAs (MicroRNA)IBA 08/2011 - 05/2010
2	Collagen Type I (Type I Collagen)IBA 03/2011 - 06/2010
1	ChemokinesIBA 10/2023
1	EndoribonucleasesIBA 10/2023
1	Hepatitis B Core AntigensIBA 03/2023
1	NF-kappa B (NF-kB)IBA 01/2023
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2023
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2023
1	InterleukinsIBA 01/2023
1	IntegrinsIBA 01/2023
1	PTX3 proteinIBA 12/2022
1	Prothrombin (Factor II)IBA 12/2022
1	Circulating Tumor DNAIBA 07/2022
1	Cell-Free Nucleic AcidsIBA 07/2022
1	TensinsIBA 07/2022
1	beta CateninIBA 07/2022
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 07/2022

Therapy/Procedure

20	Therapeutics 01/2024 - 06/2008
4	Immunotherapy 01/2023 - 09/2013
2	Drug Therapy (Chemotherapy) 12/2022 - 07/2022
1	Heart-Assist Devices 04/2024
1	Treatment Delay 11/2023
1	Transplantation 10/2023
1	Radiofrequency Ablation 12/2022